Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.46 |
| ▸ | CBFB | Q13951 | 1/20 | 0.46 |
| ▸ | RHEB | Q15382 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219757 | 0.85 | TP53 (0.63) | SMN1; SMN2HPGDKDM4ELMNAHTT | |
| SCHEMBL9216793 | 0.84 | POLB (0.58) | SMN1; SMN2HPGDKDM4ELMNAHTT | |
| SCHEMBL9681469 | 0.83 | RAB9A (0.55) | RAB9ASMN1; SMN2NPC1HPGDKDM4E | |
| SCHEMBL9683402 | 0.83 | ALDH1A1 (0.56) | SMN1; SMN2HPGDKDM4ELMNAHTT | |
| SCHEMBL9430659 | 0.83 | POLB (0.60) | SMN1; SMN2HPGDKDM4ELMNAHTT | |
| SCHEMBL9221106 | 0.83 | POLB (0.60) | SMN1; SMN2HPGDKDM4ELMNAHTT | |
| SCHEMBL9681584 | 0.82 | MAPT (0.57) | RAB9ASMN1; SMN2NPC1HPGDKDM4E | |
| SCHEMBL9682548 | 0.82 | GAA (0.59) | RAB9ASMN1; SMN2NPC1HPGDKDM4E | |
| SCHEMBL9217609 | 0.82 | RXFP1 (0.58) | SMN1; SMN2HPGDKDM4ELMNAHTT | |
| SCHEMBL9212926 | 0.80 | L3MBTL1 (0.57) | RAB9ASMN1; SMN2NPC1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |