Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29079309 | 0.77 | GABRA1 (0.45) | HPGD | |
| SCHEMBL10177266 | 0.77 | DGAT1 (0.40) | HPGD | |
| SCHEMBL30442899 | 0.77 | DGAT1 (0.40) | HPGD | |
| SCHEMBL16661274 | 0.76 | KDM4E (0.45) | HPGD | |
| SCHEMBL11623789 | 0.75 | HPGD (0.43) | HPGD | |
| SCHEMBL25791857 | 0.74 | NT5E (0.32) | — | |
| SCHEMBL9638929 | 0.73 | NISCH (0.37) | — | |
| SCHEMBL4425449 | 0.73 | — | — | |
| SCHEMBL31346275 | 0.72 | — | — | |
| SCHEMBL25196015 | 0.71 | SPR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0229922-B1 | NOVEL 2,2'-BI-1H-IMIDAZOLES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-04-15 | — | — | EP | disclosed |
| EP-0229922-A2 | Novel 2,2'-BI-1H-imidazoles | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-07-29 | — | — | EP | disclosed |