Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.44 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3610930 | 0.85 | PTPN1 (0.59) | L3MBTL1PTPN1MEN1KMT2AMAPT | |
| SCHEMBL9219744 | 0.84 | PTPN1 (0.56) | L3MBTL1PTPN1MEN1KMT2AMAPT | |
| SCHEMBL8201626 | 0.82 | L3MBTL1 (0.60) | L3MBTL1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL11745212 | 0.82 | L3MBTL1 (0.47) | L3MBTL1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL10871209 | 0.80 | RXRA (0.51) | PTPN1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL9217855 | 0.77 | IP6K1 (0.48) | L3MBTL1CNR1CNR2MEN1KMT2A | |
| SCHEMBL9222006 | 0.76 | HDAC1 (0.51) | L3MBTL1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL27350962 | 0.76 | KDM4E (0.50) | PTPN1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL30806087 | 0.76 | KDM4E (0.50) | PTPN1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL11901558 | 0.75 | MAPT (0.57) | PTPN1KMT2AMAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |