Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 2/20 | 0.48 |
| ▸ | IP6K3 | Q96PC2 | 2/20 | 0.48 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.48 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | RXRB | P28702 | 2/20 | 0.46 |
| ▸ | RXRG | P48443 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216798 | 0.84 | KDM4E (0.47) | IP6K1IP6K3IP6K2NPC1RAB9A | |
| SCHEMBL9212264 | 0.83 | KDM4E (0.55) | NPC1RAB9AHPGDSMN1; SMN2TSHR | |
| SCHEMBL9219756 | 0.83 | TP53 (0.51) | IP6K1IP6K3IP6K2RXRARXRB | |
| SCHEMBL9217844 | 0.77 | L3MBTL1 (0.49) | NPC1RAB9AHPGDSMN1; SMN2KDM4E | |
| SCHEMBL9222019 | 0.75 | NAAA (0.46) | HPGDSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL9212333 | 0.75 | MAPT (0.46) | IP6K1IP6K3IP6K2NPC1RAB9A | |
| SCHEMBL28429262 | 0.73 | KDM4E (0.72) | NPC1RAB9AHPGDSMN1; SMN2TSHR | |
| SCHEMBL31723137 | 0.73 | KDM4E (0.72) | NPC1RAB9AHPGDSMN1; SMN2TSHR | |
| SCHEMBL9218354 | 0.73 | ALDH1A1 (0.46) | RXRARXRBRXRGNPC1RAB9A | |
| SCHEMBL9217470 | 0.73 | IP6K1 (0.42) | IP6K1IP6K3IP6K2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |