Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494876 | 0.88 | ADORA3 (0.45) | NPC1CYP1A2ADORA3RAB9ATDP1 | |
| SCHEMBL10510673 | 0.78 | ADORA3 (0.44) | CYP1A2KDM4EADORA3IDO1TDO2 | |
| SCHEMBL5470573 | 0.76 | NPC1 (0.63) | NPC1CYP1A2KDM4ERAB9AGRM4 | |
| SCHEMBL31427619 | 0.72 | ALDH1A1 (0.37) | CYP1A2KDM4EADORA3TDP1CYP2A6 | |
| SCHEMBL28328752 | 0.70 | L3MBTL1 (0.44) | CYP1A2KDM4ECYP2A6L3MBTL1 | |
| Bromide SCHEMBL5045247 | 0.69 | ALDH1A1 (0.34) | CYP1A2ADORA3TDP1CYP2A6L3MBTL1 | |
| SCHEMBL31427616 | 0.68 | ALDH1A1 (0.33) | CYP1A2ADORA3L3MBTL1 | |
| SCHEMBL29526856 | 0.67 | ATM (0.51) | NPC1CYP1A2KDM4ERAB9ATDP1 | |
| SCHEMBL1169875 | 0.67 | ATM (0.51) | NPC1CYP1A2KDM4ERAB9ATDP1 | |
| SCHEMBL731645 | 0.67 | NPC1 (0.62) | NPC1CYP1A2KDM4ERAB9AGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0180492-A1 | Macropolycyclic complexes of rare earth metals and application as fluorescent labels | CIS BIO INTERNATIONAL (FR) | 1986-05-07 | — | — | EP | claimed |
| US-5432101-A | Complex consists of biologically active molecule associated by coupling or adsorption with the complex | COMPAGNIE ORIS INDUSTRIE SA (FR) | 1995-07-11 | — | — | US | disclosed |
| US-5220012-A | Macropolycyclic rare earth complexes and application as fluorescent tracers | COMPAGNIE ORIS INDUSTRIE SA (FR) | 1993-06-15 | — | — | US | disclosed |
| US-4927923-A | IMMUNOLOGY | COMPAGNIE ORIS INDUSTRIES (FR) | 1990-05-22 | — | — | US | disclosed |