Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8812869 | 0.82 | LMNA (0.39) | TAS2R8ALDH1A1MAPTNPC1MEN1 | |
| SCHEMBL8579780 | 0.76 | GRM4 (0.52) | ESR1ESR2XIAPBIRC2MAPT | |
| SCHEMBL10378643 | 0.70 | DRD2 (0.37) | MAPTMEN1KMT2A | |
| SCHEMBL10392498 | 0.66 | ESR1 (0.52) | ESR1ESR2 | |
| SCHEMBL8581414 | 0.65 | ESR1 (0.41) | ESR1ESR2HDAC6 | |
| SCHEMBL8583544 | 0.64 | ESR1 (0.62) | ESR1ESR2 | |
| SCHEMBL10749668 | 0.63 | BMPR1B (0.48) | ESR1ESR2ALDH1A1 | |
| SCHEMBL7212105 | 0.62 | L3MBTL1 (0.42) | HDAC6L3MBTL1PARP1PARP2 | |
| SCHEMBL10718524 | 0.61 | L3MBTL1 (0.42) | HDAC6L3MBTL1ALDH1A1MAPTPARP1 | |
| SCHEMBL13853160 | 0.61 | HDAC6 (0.50) | HDAC6L3MBTL1PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656892-A1 | HERBICIDAL 2- (4-HETEROCYCLIC-PHENOXYMETHYL)PHENOXY]-ALKANOATES | FMC CORPORATION (US) | 1995-06-14 | — | — | EP | disclosed |