SCHEMBL921923

SCHEMBL921923

Nc1ncccc1C(=O)NCc1cc(F)cc(F)c1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 1/20 0.57
KMT2A Q03164 1/20 0.54
MET P08581 1/20 0.53
AURKA O14965 2/20 0.49
PRKCI P41743 2/20 0.49
PDPK1 O15530 1/20 0.48
NSD2 O96028 1/20 0.47
NAPRT Q6XQN6 1/20 0.46
ROCK1 Q13464 1/20 0.46
RPS6KB1 P23443 1/20 0.46
AURKB Q96GD4 1/20 0.46
MAPK8 P45983 1/20 0.45
ATM Q13315 1/20 0.45
P2RX7 Q99572 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL922542 0.90 ROCK1 (0.57) KMT2AAURKAPDPK1NSD2ROCK1
SCHEMBL923044 0.88 KMT2A (0.70) EGLN1KMT2ANSD2ROCK1
SCHEMBL923307 0.87 KMT2A (0.51) EGLN1KMT2APDPK1MAPK8
SCHEMBL922067 0.84 MET (0.56) KMT2AMETAURKAPRKCIPDPK1
SCHEMBL922492 0.83 NSD2 (0.66) EGLN1KMT2APRKCINSD2NAPRT
SCHEMBL920343 0.81 KMT2A (0.61) KMT2AMAPK8
SCHEMBL923100 0.81 HPGD (0.51) KMT2AROCK1RPS6KB1MAPK8
SCHEMBL1680671 0.81 MAOB (0.54)
SCHEMBL921272 0.81 MT-CO2 (0.54) EGLN1KMT2APRKCINSD2NAPRT
SCHEMBL27824616 0.81 NSD2 (0.56) EGLN1KMT2APRKCINSD2NAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 EGLN1 430/4885KMT2A 2469/4885MET 3120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.