Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 14/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214645 | 0.76 | NR3C1 (0.45) | NR3C1PGRNR3C2AR | |
| Hydrochloric Acid SCHEMBL9216254 | 0.74 | ADRA2C (0.62) | ADRB3ADRA2CADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL9215546 | 0.72 | ADRA2C (0.54) | ADRB3ADRA2CADRA1AADRA1B | |
| SCHEMBL9218206 | 0.70 | NR3C1 (0.44) | NR3C1PGRNR3C2AR | |
| SCHEMBL5674482 | 0.70 | ADRB3 (0.58) | ADRB3 | |
| SCHEMBL5674486 | 0.68 | — | — | |
| SCHEMBL9214656 | 0.67 | ADRB3 (0.47) | ADRB3 | |
| SCHEMBL9216269 | 0.67 | NR3C1 (0.44) | NR3C1PGRNR3C2AR | |
| SCHEMBL13993320 | 0.66 | KDM4E (0.70) | — | |
| SCHEMBL14274010 | 0.66 | KDM4E (0.70) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538469-B1 | SULFONANILIDE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU CO LTD (JP) | 1995-09-27 | — | — | EP | disclosed |
| US-5360822-A | FOR TREATING URINARY INCONTINENCE IN ANIMALS AND HUMANS | NIPPON SHINYAKU CO. LTD. (JP) | 1994-11-01 | — | — | US | disclosed |
| EP-0538469-A1 | SULFONANILIDE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-04-28 | — | — | EP | disclosed |