Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 13/20 | 0.39 |
| ▸ | NPC1 | O15118 | 12/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.37 |
| ▸ | RELA | Q04206 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | HCK | P08631 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215756 | 0.87 | SRC (0.45) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9221670 | 0.84 | RAB9A (0.45) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9219561 | 0.84 | RAB9A (0.52) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9220305 | 0.84 | RAB9A (0.43) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9213350 | 0.84 | RAB9A (0.52) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9172768 | 0.84 | RAB9A (0.55) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9220405 | 0.83 | RAB9A (0.50) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9219429 | 0.82 | PIK3CD (0.43) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9219419 | 0.81 | ALDH1A1 (0.34) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9217938 | 0.81 | CYP11B2 (0.46) | LCKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269859-B2 | Pyrazolotriazine compounds | OTSUKA PHARMA CO LTD (JP) | 1995-10-18 | — | — | EP | disclosed |
| US-4824834-A | TREATING GOUT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-04-25 | — | — | US | disclosed |
| EP-0269859-A2 | Pyrazolotriazine compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-08 | — | — | EP | disclosed |