Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 4/20 | 0.32 |
| ▸ | PYGM | P11217 | 4/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758043 | 0.74 | CRHBP (0.40) | TP53POLBHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL4756140 | 0.73 | CRHBP (0.35) | NPC1TP53HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL30516327 | 0.67 | PYGL (0.34) | PYGLPYGMOPRM1OPRD1OPRK1 | |
| SCHEMBL30656597 | 0.67 | HTR1A (0.39) | PYGLPYGMOPRM1OPRD1OPRK1 | |
| SCHEMBL8535870 | 0.66 | KMT2A (0.35) | NPC1TP53POLBHPGDRAB9A | |
| SCHEMBL30516330 | 0.64 | PYGL (0.32) | PYGLPYGMPOLB | |
| SCHEMBL30516333 | 0.64 | PYGL (0.32) | PYGLPYGMPOLB | |
| SCHEMBL3393583 | 0.64 | TSHR (0.40) | TP53POLBHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL2365028 | 0.64 | TSHR (0.37) | PYGLPYGMCNR1TP53HPGD | |
| SCHEMBL6825360 | 0.63 | HTR1A (0.37) | PYGLPYGMOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657433-A1 | Dihydropyridines with substituted esters showing cerebral activity | BAYER AG (DE) | 1995-06-14 | — | — | EP | disclosed |