Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.67 |
| ▸ | FAAH | O00519 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8821944 | 1.00 | NOD1 (0.67) | NOD1FAAHALDH1A1MAPTGLO1 | |
| SCHEMBL8821918 | 1.00 | NOD1 (0.67) | NOD1FAAHALDH1A1MAPTGLO1 | |
| SCHEMBL8821938 | 0.87 | NOD1 (0.53) | NOD1FAAHALDH1A1MAPTGLO1 | |
| SCHEMBL29430995 | 0.85 | NOD1 (0.51) | NOD1FAAHALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL31622131 | 0.83 | NOD1 (0.51) | NOD1FAAHALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6129561 | 0.83 | NOD1 (0.61) | NOD1SLC6A5 | |
| SCHEMBL2508780 | 0.83 | NOD1 (0.61) | NOD1SLC6A5 | |
| SCHEMBL11103615 | 0.82 | NOD1 (0.59) | NOD1ECE1DPP4ERAP2ERAP1 | |
| SCHEMBL4217551 | 0.82 | NOD1 (0.59) | NOD1ECE1DPP4ERAP2ERAP1 | |
| SCHEMBL7927426 | 0.82 | NOD1 (0.59) | NOD1ECE1DPP4ERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416070-A | Composition for macrophage activation | IMMUNOTHERAPEUTICS, INC. (US) | 1995-05-16 | — | — | US | disclosed |
| EP-0527803-A1 | COMPOSITION FOR MACROPHAGE ACTIVATION. | IMMUNOTHERAPEUTICS INC (US) | 1993-02-24 | — | — | EP | disclosed |
| WO-1991016347-A1 | COMPOSITION FOR MACROPHAGE ACTIVATION | IMMUNOTHERAPEUTICS, INC. (US) | 1991-10-31 | — | — | WO | disclosed |