SCHEMBL29430995

SCHEMBL29430995

CC(=O)N[C@@H](C)C(=O)N[C@H](CCC(=O)N[C@@H](C)C(=O)O)C(N)=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NOD1 Q9Y239 2/20 0.51
▸ FAAH O00519 3/20 0.40
▸ NOD2 Q9HC29 1/20 0.39
▸ SIRT5 Q9NXA8 3/20 0.39
▸ ALDH1A1 P00352 2/20 0.38
▸ MAPT P10636 1/20 0.38
▸ ESR1 P03372 1/20 0.37
▸ PGR P06401 1/20 0.37
▸ HTR1A P08908 1/20 0.37
▸ ADORA3 P0DMS8 1/20 0.37
▸ AR P10275 1/20 0.37
▸ CHRM1 P11229 1/20 0.37
▸ TBXA2R P21731 1/20 0.37
▸ PTGS1 P23219 1/20 0.37
▸ ADRA1A P35348 1/20 0.37
▸ KCNH2 Q12809 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ GNPAT O15228 1/20 0.35
▸ SLC6A5 Q9Y345 1/20 0.35
▸ PTPN1 P18031 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8821944 0.85 NOD1 (0.67) NOD1FAAHALDH1A1MAPTPTGS1
SCHEMBL9220222 0.85 NOD1 (0.67) NOD1FAAHALDH1A1MAPTPTGS1
SCHEMBL8821918 0.85 NOD1 (0.67) NOD1FAAHALDH1A1MAPTPTGS1
SCHEMBL11596384 0.85 NOD2 (0.49) NOD1NOD2SIRT5GNPATPTPN1
SCHEMBL10778212 0.83 NOD1 (0.59) NOD1SIRT5ESR1PGRHTR1A
SCHEMBL11120073 0.82 NOD1 (0.46) NOD1
SCHEMBL8821938 0.82 NOD1 (0.53) NOD1FAAHALDH1A1MAPTPTGS1
SCHEMBL31622131 0.81 NOD1 (0.51) NOD1FAAHALDH1A1MAPTSMN1; SMN2
SCHEMBL22462688 0.80 ALDH1A1 (0.52) NOD1FAAHALDH1A1MAPTSMN1; SMN2
SCHEMBL22462686 0.80 ALDH1A1 (0.52) NOD1FAAHALDH1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4487869-A2 RNA ENCODING A TUMOR ANTIGEN CureVac SE (DE) 2025-01-08 — — EP claimed
US-20240091344-A1 MERS CORONAVIRUS VACCINE CureVac SE (DE) 2024-03-21 — — US claimed
EP-3595715-B1 RNA VACCINE AND IMMUNE CHECKPOINT INHIBITORS FOR COMBINED ANTICANCER THERAPY CureVac SE (DE) 2026-05-27 — — EP disclosed
US-20260137768-A1 ZIKA VIRUS VACCINE CureVac SE (DE) 2026-05-21 — — US disclosed
US-20260137769-A1 NUCLEIC ACID MOLECULES AND USES THEREOF CureVac SE (DE) 2026-05-21 — — US disclosed
US-12618060-B2 Nucleic acid molecules CureVac SE (DE) 2026-05-05 — — US disclosed
US-20260102489-A1 COMBINATION OF VACCINATION AND INHIBITION OF THE PD-1 PATHWAY CureVac SE (DE) 2026-04-16 — — US disclosed
US-20260090989-A1 LIPID NANOPARTICLE mRNA VACCINES CureVac SE (DE) 2026-04-02 — — US disclosed
US-20260091101-A1 BUNYAVIRALES VACCINE CureVac SE (DE) 2026-04-02 — — US disclosed
US-20260071224-A1 ARTIFICIAL NUCLEIC ACID MOLECULES FOR IMPROVED PROTEIN EXPRESSION CureVac SE (DE) 2026-03-12 — — US disclosed
US-12569549-B2 Flavivirus vaccine CureVac SE (DE) 2026-03-10 — — US disclosed
US-11345920-B2 Artificial nucleic acid molecules for improved protein expression CUREVAC AG (DE) 2022-05-31 — — US disclosed
US-20220152193-A1 COMBINATION VACCINE CUREVAC AG (DE) 2022-05-19 — — US disclosed
US-20220144877-A1 RNA SEQUENCE ADAPTATION CUREVAC AG (DE) 2022-05-12 — — US disclosed
US-20220136001-A1 ARTIFICIAL NUCLEIC ACID MOLECULES CUREVAC AG (DE) 2022-05-05 — — US disclosed
CN-114381470-A Artificial nucleic acid molecules 库瑞瓦格股份公司 2022-04-22 — — CN disclosed
US-20220096616-A1 COMPOSITION FOR TREATING LUNG CANCER, PARTICULARLY OF NON-SMALL LUNG CANCERS (NSCLC) CUREVAC AG (DE) 2022-03-31 — — US disclosed
US-11286492-B2 Artificial nucleic acid molecules for improved protein expression CUREVAC AG (DE) 2022-03-29 — — US disclosed
US-20220090092-A1 ARTIFICIAL NUCLEIC ACID MOLECULES FOR IMPROVED PROTEIN EXPRESSION CUREVAC AG (DE) 2022-03-24 — — US disclosed
CN-106102770-B Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof 辉瑞公司 2022-03-22 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11345920-B2 Artificial nucleic acid molecules for improved protein expression NSUN3, CPSF6, CPSF1 NOD1 2300/4885FAAH 4620/4885NOD2 2417/4885
US-12618060-B2 Nucleic acid molecules TP53, MICA, TAP1 NOD1 3708/4885FAAH 4347/4885NOD2 3551/4885
US-20220152193-A1 COMBINATION VACCINE FURIN, HELZ, SF3B5 NOD1 700/4885FAAH 3711/4885NOD2 827/4885
US-20220090092-A1 ARTIFICIAL NUCLEIC ACID MOLECULES FOR IMPROVED PROTEIN EXPRESSION CPSF6, CPSF1, RNMT NOD1 2504/4885FAAH 4423/4885NOD2 2668/4885
US-20260102489-A1 COMBINATION OF VACCINATION AND INHIBITION OF THE PD-1 PATHWAY PDCD1, PDCD1LG2, CD274 NOD1 1002/4885FAAH 4165/4885NOD2 1184/4885
US-11286492-B2 Artificial nucleic acid molecules for improved protein expression CPSF6, CPSF1, RNMT NOD1 2504/4885FAAH 4423/4885NOD2 2668/4885
US-20260071224-A1 ARTIFICIAL NUCLEIC ACID MOLECULES FOR IMPROVED PROTEIN EXPRESSION RNGTT, RNMT, NSUN3 NOD1 261/4885FAAH 3910/4885NOD2 598/4885
US-20240091344-A1 MERS CORONAVIRUS VACCINE SARS1, RNMT, ACE2 NOD1 1421/4885FAAH 2291/4885NOD2 1396/4885
US-20260091101-A1 BUNYAVIRALES VACCINE RNGTT, RNMT, TIA1 NOD1 941/4885FAAH 4329/4885NOD2 1499/4885
US-12569549-B2 Flavivirus vaccine LNPK, PCTP, CETP NOD1 668/4885FAAH 1798/4885NOD2 2287/4885
US-20260137768-A1 ZIKA VIRUS VACCINE ADAR, RNGTT, UPF1 NOD1 252/4885FAAH 4149/4885NOD2 1066/4885
US-20260137769-A1 NUCLEIC ACID MOLECULES AND USES THEREOF RNMT, RNGTT, NSUN3 NOD1 63/4885FAAH 4607/4885NOD2 99/4885
US-20260090989-A1 LIPID NANOPARTICLE mRNA VACCINES RNMT, NSUN3, SARNP NOD1 1744/4885FAAH 1529/4885NOD2 2458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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