SCHEMBL9220318

SCHEMBL9220318

CCCCCC(CC)/C(=C/c1ccc(OC)cc1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.46
MEN1 O00255 1/20 0.43
CYP2D6 P10635 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 1/20 0.43
TAS1R3 Q7RTX0 3/20 0.43
TAS1R1 Q7RTX1 3/20 0.43
MMP9 P14780 4/20 0.41
MMP13 P45452 4/20 0.41
ADAM17 P78536 4/20 0.41
MMP1 P03956 4/20 0.41
MMP2 P08253 1/20 0.40
MMP3 P08254 1/20 0.40
LMNA P02545 1/20 0.40
THRB P10828 1/20 0.39
ATM Q13315 1/20 0.39
PPARA Q07869 1/20 0.39
AKR1C3 P42330 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9220321 1.00 TDP1 (0.46) TDP1MEN1CYP2D6HTTKMT2A
SCHEMBL25303957 1.00 TDP1 (0.46) TDP1MEN1CYP2D6HTTKMT2A
SCHEMBL7266955 0.78 TDP1 (0.54) TDP1MMP9MMP1MMP2MMP3
SCHEMBL7773761 0.78 ALOX5 (0.43) TDP1MEN1CYP2D6HTTKMT2A
2-Ethylhexanoic Acid SCHEMBL4018852 0.75 CA2 (0.43) TDP1TAS1R3TAS1R1MMP2MMP3
SCHEMBL490213 0.74 THRB (0.50) TAS1R3TAS1R1THRBATMAKR1C3
SCHEMBL4879128 0.74 THRB (0.50) TAS1R3TAS1R1THRBATMAKR1C3
SCHEMBL4906426 0.74 THRB (0.50) TAS1R3TAS1R1THRBATMAKR1C3
SCHEMBL2490383 0.74 ALOX5 (0.54) TDP1LMNATHRBATM
SCHEMBL5198950 0.73 TDP1 (0.56) TDP1TAS1R3TAS1R1MMP9MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3024429-A2 UV COMPOSITIONS HAVING LOW ACTIVE CONCENTRATIONS AND HIGH IN VIVO SPF The Procter & Gamble Company (US) 2016-06-01 EP claimed
US-9044405-B2 Composition having a reduced exotherm in actinic curing of urethane (meth)acrylate oligomers on fingernails O P I PRODUCTS, INC. (US) 2015-06-02 US claimed
WO-2015013198-A2 UV COMPOSITIONS HAVING LOW ACTIVE CONCENTRATIONS AND HIGH IN VIVO SPF THE PROCTER & GAMBLE COMPANY (US) 2015-01-29 WO claimed
US-20150023895-A1 UV Compositions Having Low Active Concentrations and High In Vivo SPF THE PROCTER & GAMBLE COMPANY 2015-01-22 US claimed
WO-2014134009-A1 COMPOSITION HAVING A REDUCED EXOTHERM IN ACTINIC CURING OF URETHANE (METH)ACRYLATE OLIGOMERS ON FINGERNAILS O P I PRODUCTS, INC. (US) 2014-09-04 WO claimed
US-20140242011-A1 COMPOSITION HAVING A REDUCED EXOTHERM IN ACTINIC CURING OF URETHANE (METH)ACRYLATE OLIGOMERS ON FINGERNAILS O P I PRODUCTS, INC. (US) 2014-08-28 US claimed
US-5468492-A Plant extract for treatment of hair loss BIOGAL GYOGYSZERGYAR RT (HU) 1995-11-21 US claimed
US-12396965-B2 Putrescine topical barrier formulation VIVIER CANADA INC. (CA) 2025-08-26 US disclosed
US-20240293340-A1 PUTRESCINE TOPICAL BARRIER FORMULATION VIVIER CANADA INC. (CA) 2024-09-05 US disclosed
US-20230321006-A1 PUTRESCINE TOPICAL BARRIER FORMULATION VIVIER CANADA INC. (CA) 2023-10-12 US disclosed
US-20210251920-A1 PUTRESCINE TOPICAL BARRIER FORMULATION VIVIER CANADA INC. (CA) 2021-08-19 US disclosed
US-20200281872-A1 PUTRESCINE TOPICAL BARRIER FORMULATION VIVIER CANADA INC. (CA) 2020-09-10 US disclosed
US-20190314299-A1 PUTRESCINE TOPICAL BARRIER FORMULATION VIVIER CANADA INC. (CA) 2019-10-17 US disclosed
US-20150023895-A1 UV Compositions Having Low Active Concentrations and High In Vivo SPF THE PROCTER & GAMBLE COMPANY 2015-01-22 US disclosed
US-20150023895-A1 UV Compositions Having Low Active Concentrations and High In Vivo SPF THE PROCTER & GAMBLE COMPANY 2015-01-22 US disclosed
WO-2014134009-A1 COMPOSITION HAVING A REDUCED EXOTHERM IN ACTINIC CURING OF URETHANE (METH)ACRYLATE OLIGOMERS ON FINGERNAILS O P I PRODUCTS, INC. (US) 2014-09-04 WO disclosed
US-20140242011-A1 COMPOSITION HAVING A REDUCED EXOTHERM IN ACTINIC CURING OF URETHANE (METH)ACRYLATE OLIGOMERS ON FINGERNAILS O P I PRODUCTS, INC. (US) 2014-08-28 US disclosed
US-5468492-A Plant extract for treatment of hair loss BIOGAL GYOGYSZERGYAR RT (HU) 1995-11-21 US disclosed
EP-0497952-A1 COMPOSITION FOR THE TOPICAL TREATMENT OF PSORIASIS BIOGAL GYOGYSZERGYAR RT. (HU) 1992-08-12 EP disclosed
WO-1992003142-A1 COMPOSITION FOR THE TOPICAL TREATMENT OF PSORIASIS BIOGAL Gyógyszergyár Rt. (HU) 1992-03-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150023895-A1 UV Compositions Having Low Active Concentrations and High In Vivo SPF F10, PAH, RAD50 TDP1 826/4885MEN1 3948/4885CYP2D6 1287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.