SCHEMBL922041

SCHEMBL922041

Nc1nc(F)ccc1C(=O)NCc1ccc(Oc2cc(C(F)(F)F)ccc2F)cc1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 8/20 0.46
PPARG P37231 6/20 0.46
PPARD Q03181 6/20 0.46
MAPK14 Q16539 2/20 0.46
SORT1 Q99523 1/20 0.44
CHEK2 O96017 1/20 0.42
KCNQ3 O43525 1/20 0.42
KCNQ2 O43526 1/20 0.42
PTGER4 P35408 2/20 0.42
PTGER2 P43116 1/20 0.42
RECQL P46063 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921739 0.92 PPARA (0.50) PPARAPPARGPPARDMAPK14SORT1
SCHEMBL920019 0.91 PPARA (0.49) PPARAPPARGPPARDMAPK14SORT1
SCHEMBL919953 0.89 MAPK14 (0.58) PPARAPPARGPPARDMAPK14SORT1
SCHEMBL921159 0.89 HTR2C (0.43) PPARAPPARGPPARDMAPK14PTGER4
SCHEMBL922608 0.87 PPARA (0.46) PPARAPPARGPPARDMAPK14SORT1
SCHEMBL920958 0.86 MAPK14 (0.47) PPARAPPARGPPARDMAPK14SORT1
SCHEMBL920920 0.85 MAPK14 (0.53) PPARAPPARGPPARDMAPK14RECQL
SCHEMBL921339 0.85 KLKB1 (0.42) PPARAPPARGPPARDMAPK14PTGER4
SCHEMBL922230 0.84 MAPK14 (0.43) MAPK14PTGER4PTGER2
SCHEMBL921057 0.84 L3MBTL1 (0.48) MAPK14PTGER4PTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 PPARA 494/4885PPARG 391/4885PPARD 360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.