Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 2/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.36 |
| ▸ | PYGM | P11217 | 2/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364254 | 0.90 | HSP90AA1 (0.40) | GPBAR1HSP90AA1HSP90AB1KMT2ALMNA | |
| SCHEMBL9222124 | 0.89 | PYGM (0.37) | PYGMPYGLKMT2AATMLMNA | |
| SCHEMBL9364532 | 0.84 | POLB (0.43) | APOBEC3AAPOBEC3GHSP90AA1HSP90AB1KMT2A | |
| SCHEMBL9213691 | 0.82 | PYGM (0.50) | APOBEC3AAPOBEC3GPYGMPYGLGPBAR1 | |
| SCHEMBL9364248 | 0.82 | HSP90AA1 (0.44) | GPBAR1HSP90AA1HSP90AB1KMT2ALMNA | |
| SCHEMBL9363806 | 0.79 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1LMNATSHRPOLB | |
| SCHEMBL9222084 | 0.79 | CACNA1F (0.41) | GPBAR1KMT2ALMNAMEN1CYP1A2 | |
| SCHEMBL9215408 | 0.79 | KDM4E (0.37) | GPBAR1KMT2AATMLMNAMEN1 | |
| SCHEMBL9364022 | 0.79 | KDM4E (0.41) | GPBAR1ATMCYP3A4CYP2C9TSHR | |
| SCHEMBL9363808 | 0.79 | HSP90AA1 (0.42) | HSP90AA1HSP90AB1LMNATSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525568-B1 | N-Alkylated 1,4-dihydropyridine carboxylicacid ester derivatives | BAYER AG (DE) | 1995-05-10 | — | — | EP | claimed |
| EP-0525568-A1 | N-Alkylated 1,4-dihydropyridine carboxylicacid ester derivatives | BAYER AG (DE) | 1993-02-03 | — | — | EP | claimed |
| EP-0525568-A1 | N-Alkylated 1,4-dihydropyridine carboxylicacid ester derivatives | BAYER AG (DE) | 1993-02-03 | — | — | EP | disclosed |