Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 2/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215408 | 0.91 | KDM4E (0.37) | KDM4ETDP1LMNAALDH1A1GAA | |
| SCHEMBL9220730 | 0.89 | APOBEC3A (0.36) | PYGMPYGLKDM4ETDP1LMNA | |
| SCHEMBL9220816 | 0.88 | LMNA (0.35) | KDM4ETDP1LMNAALDH1A1GAA | |
| SCHEMBL9220835 | 0.84 | PYGM (0.49) | PYGMPYGLKDM4ETDP1LMNA | |
| SCHEMBL9364254 | 0.79 | HSP90AA1 (0.40) | KDM4ETDP1LMNAALDH1A1GAA | |
| SCHEMBL9222084 | 0.78 | CACNA1F (0.41) | KDM4ETDP1LMNAALDH1A1GAA | |
| SCHEMBL9214880 | 0.76 | HPGD (0.46) | KDM4ELMNAALDH1A1HPGDPOLB | |
| SCHEMBL9222512 | 0.76 | HTT (0.47) | PYGMPYGLKDM4ETDP1LMNA | |
| SCHEMBL23686114 | 0.76 | LMNA (0.57) | KDM4ETDP1LMNAALDH1A1GAA | |
| SCHEMBL9220779 | 0.76 | ADRA2A (0.35) | KDM4ELMNAALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525568-B1 | N-Alkylated 1,4-dihydropyridine carboxylicacid ester derivatives | BAYER AG (DE) | 1995-05-10 | — | — | EP | claimed |
| EP-0525568-A1 | N-Alkylated 1,4-dihydropyridine carboxylicacid ester derivatives | BAYER AG (DE) | 1993-02-03 | — | — | EP | claimed |
| EP-0525568-B1 | N-Alkylated 1,4-dihydropyridine carboxylicacid ester derivatives | BAYER AG (DE) | 1995-05-10 | — | — | EP | disclosed |
| EP-0525568-A1 | N-Alkylated 1,4-dihydropyridine carboxylicacid ester derivatives | BAYER AG (DE) | 1993-02-03 | — | — | EP | disclosed |