Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9222124 | 0.91 | PYGM (0.37) | KDM4ETDP1LMNAMEN1CYP1A2 | |
| SCHEMBL9220816 | 0.89 | LMNA (0.35) | KDM4ETDP1LMNAMEN1CYP1A2 | |
| SCHEMBL9364254 | 0.89 | HSP90AA1 (0.40) | KDM4ETDP1LMNAMEN1CYP1A2 | |
| SCHEMBL9222084 | 0.87 | CACNA1F (0.41) | KDM4ETDP1LMNAMEN1CYP1A2 | |
| SCHEMBL9214880 | 0.85 | HPGD (0.46) | KDM4ELMNAMEN1CYP1A2CYP3A4 | |
| SCHEMBL9222512 | 0.83 | HTT (0.47) | KDM4ETDP1LMNAMEN1CYP1A2 | |
| SCHEMBL9220779 | 0.83 | ADRA2A (0.35) | KDM4ELMNAMEN1CYP1A2CYP3A4 | |
| SCHEMBL9364248 | 0.80 | HSP90AA1 (0.44) | KDM4ETDP1LMNAKMT2ATSHR | |
| SCHEMBL9220730 | 0.79 | APOBEC3A (0.36) | KDM4ETDP1LMNAMEN1CYP1A2 | |
| SCHEMBL9363806 | 0.77 | HSP90AA1 (0.39) | KDM4ETDP1LMNATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525568-B1 | N-Alkylated 1,4-dihydropyridine carboxylicacid ester derivatives | BAYER AG (DE) | 1995-05-10 | — | — | EP | claimed |
| EP-0525568-A1 | N-Alkylated 1,4-dihydropyridine carboxylicacid ester derivatives | BAYER AG (DE) | 1993-02-03 | — | — | EP | claimed |
| EP-0525568-B1 | N-Alkylated 1,4-dihydropyridine carboxylicacid ester derivatives | BAYER AG (DE) | 1995-05-10 | — | — | EP | disclosed |
| EP-0525568-A1 | N-Alkylated 1,4-dihydropyridine carboxylicacid ester derivatives | BAYER AG (DE) | 1993-02-03 | — | — | EP | disclosed |