Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | FAAH | O00519 | 2/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.54 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.51 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8383184 | 0.85 | CERT1 (0.67) | FAAHLPAR1LPAR3EPHX2CERT1 | |
| SCHEMBL7765658 | 0.85 | CERT1 (0.67) | FAAHLPAR1LPAR3EPHX2CERT1 | |
| SCHEMBL7765661 | 0.85 | CERT1 (0.67) | FAAHLPAR1LPAR3EPHX2CERT1 | |
| SCHEMBL8342096 | 0.85 | CERT1 (0.67) | FAAHLPAR1LPAR3EPHX2CERT1 | |
| SCHEMBL9753165 | 0.84 | ITGB3 (0.61) | FAAHLPAR1LPAR3EPHX2CERT1 | |
| SCHEMBL9753163 | 0.84 | ITGB3 (0.61) | FAAHLPAR1LPAR3EPHX2CERT1 | |
| SCHEMBL9752875 | 0.84 | ITGB3 (0.61) | FAAHLPAR1LPAR3EPHX2CERT1 | |
| SCHEMBL9752873 | 0.84 | ITGB3 (0.61) | FAAHLPAR1LPAR3EPHX2CERT1 | |
| SCHEMBL12294985 | 0.83 | HPGD (0.70) | HPGDPSMB5 | |
| SCHEMBL9752931 | 0.82 | ENPP2 (0.55) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499521-B1 | Inhibitors of N-myristoyltransferase, their preparation process and pharmaceutical compositions containing them | ADIR (FR) | 1995-06-14 | — | — | EP | claimed |