Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 4/20 | 0.49 |
| ▸ | PYGL | P06737 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9222512 | 0.90 | HTT (0.47) | PYGMPYGLLMNAMEN1CYP1A2 | |
| SCHEMBL9213691 | 0.89 | PYGM (0.50) | PYGMPYGLLMNAMEN1CYP1A2 | |
| SCHEMBL9223427 | 0.86 | LMNA (0.42) | PYGMPYGLLMNAMEN1CYP1A2 | |
| SCHEMBL23686114 | 0.85 | LMNA (0.57) | LMNAMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9222124 | 0.84 | PYGM (0.37) | PYGMPYGLLMNAMEN1CYP1A2 | |
| SCHEMBL23686213 | 0.79 | HTT (0.51) | PYGMPYGLLMNAMEN1CYP1A2 | |
| SCHEMBL9119964 | 0.78 | HTT (0.48) | PYGMPYGLLMNAMEN1CYP1A2 | |
| SCHEMBL9217138 | 0.77 | HTT (0.51) | PYGMPYGLLMNAMEN1CYP1A2 | |
| SCHEMBL23686215 | 0.76 | HTT (0.53) | PYGMPYGLLMNAMEN1CYP1A2 | |
| SCHEMBL9215408 | 0.76 | KDM4E (0.37) | LMNAMEN1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525568-B1 | N-Alkylated 1,4-dihydropyridine carboxylicacid ester derivatives | BAYER AG (DE) | 1995-05-10 | — | — | EP | claimed |
| US-5328931-A | Nervous sytem disorders, cognition activators | BAYER AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | claimed |
| US-5328931-A | Nervous sytem disorders, cognition activators | BAYER AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | disclosed |