SCHEMBL922089

SCHEMBL922089

N#Cc1cccc(Oc2ccc3ccccc3c2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 2/20 0.49
PDE4A P27815 1/20 0.49
PDE4C Q08493 1/20 0.49
PDE4D Q08499 1/20 0.49
PGR P06401 1/20 0.47
MAP4K4 O95819 1/20 0.44
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43
GAA P10253 1/20 0.43
RCE1 Q9Y256 1/20 0.43
PIN1 Q13526 1/20 0.43
CHEK2 O96017 1/20 0.43
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2A6 P11509 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10923033 0.87 PDE4A (0.55) PDE4BPDE4APDE4CPDE4DPGR
SCHEMBL8379001 0.87 PDE4A (0.54) PDE4BPDE4APDE4CPDE4DPGR
SCHEMBL921076 0.85 CYP19A1 (0.50) PDE4BPDE4APDE4CPDE4DMEN1
SCHEMBL30358273 0.85 PGR (0.55) PDE4BPDE4APDE4CPDE4DPGR
SCHEMBL7186441 0.85 PGR (0.55) PDE4BPDE4APDE4CPDE4DPGR
Water SCHEMBL29061097 0.85 PGR (0.55) PDE4BPDE4APDE4CPDE4DPGR
SCHEMBL27839327 0.85 PDE4A (0.53) PDE4BPDE4APDE4CPDE4DPGR
SCHEMBL8432101 0.84 AR (0.49) PDE4BPDE4APDE4CPDE4DPGR
SCHEMBL7072557 0.81 PDE4A (0.50) PDE4BPDE4APDE4CPDE4DPGR
SCHEMBL7069974 0.81 PDE4A (0.50) PDE4BPDE4APDE4CPDE4DPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101951771-A Composition for agricultural use for controlling or preventing plant diseases caused by plant pathogens SUMITOMO CHEMICAL CO 2011-01-19 CN disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 PDE4B 4455/4885PDE4A 4539/4885PDE4C 4591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.