Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 9/20 | 0.41 |
| ▸ | NPC1 | O15118 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220694 | 0.88 | MAPT (0.45) | TP53RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9227443 | 0.86 | RARB (0.51) | RAB9ANPC1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9229844 | 0.85 | RARB (0.56) | RAB9ANPC1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9227800 | 0.84 | RARB (0.59) | RAB9ANPC1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9229100 | 0.84 | RARB (0.59) | RAB9ANPC1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9006509 | 0.78 | RAB9A (0.45) | RAB9ANPC1SMN1; SMN2MAPTTHRB | |
| SCHEMBL7513574 | 0.77 | NQO1 (0.52) | TP53RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL8077057 | 0.77 | CLK4 (0.58) | TP53RAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9062115 | 0.76 | RXRA (0.48) | RAB9ANPC1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9061744 | 0.75 | RXRA (0.49) | TP53RAB9ANPC1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403512-A | Fluorovinyloxybenzenes having low viscosity, stability, high; dielectric anisotropy and good low temperature behavior; displays; twisted cells | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-04-04 | — | — | US | disclosed |