SCHEMBL9006509

SCHEMBL9006509

CCc1ccc(OC(F)=C(F)F)cc1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.45
SMN1; SMN2 Q16637 4/20 0.43
CYP2C19 P33261 1/20 0.43
ALDH1A1 P00352 3/20 0.41
POLB P06746 1/20 0.40
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
LPL P06858 1/20 0.39
LIPG Q9Y5X9 1/20 0.39
LMNA P02545 2/20 0.37
THRB P10828 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
NPC1 O15118 2/20 0.37
PPARG P37231 1/20 0.37
PPARA Q07869 1/20 0.37
KMT2A Q03164 1/20 0.37
ELANE P08246 1/20 0.36
HSP90AA1 P07900 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5650004 0.86 RAB9A (0.35) RAB9ASMN1; SMN2CYP2C19ALDH1A1POLB
SCHEMBL12903696 0.84 THRB (0.54) RAB9ASMN1; SMN2ALDH1A1LPLLIPG
SCHEMBL4530562 0.82 RAB9A (0.35) RAB9ASMN1; SMN2ALDH1A1POLBLMNA
SCHEMBL4711303 0.81 LTA4H (0.47) THRBPPARGPPARAKMT2AELANE
SCHEMBL8731268 0.79 TRPA1 (0.36) ALDH1A1THRBKMT2AELANE
SCHEMBL12888778 0.79 ESR1 (0.48) THRBPPARGPPARAELANE
SCHEMBL13669682 0.79 PTGS2 (0.47) LMNA
SCHEMBL9223992 0.78 TP53 (0.43) RAB9ASMN1; SMN2CYP2C19ALDH1A1LMNA
SCHEMBL9549801 0.77 MAPK1 (0.42) SMN1; SMN2ALDH1A1POLBKMT2A
SCHEMBL4260460 0.76 THRB (0.39) THRBKMT2AELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110330710-B Pressure-resistant PE pipe and preparation method thereof 福建亚通新材料科技股份有限公司 2021-10-26 CN claimed
CN-113214425-A Modified polytetrafluoroethylene and preparation method and application thereof 深圳市圣一科技有限公司 2021-08-06 CN claimed
CN-110828872-B High-temperature proton exchange membrane for fuel cell and preparation method thereof 江苏擎动新能源科技有限公司 2021-03-12 CN claimed
CN-110828872-A High-temperature proton exchange membrane for fuel cell and preparation method thereof 刘艳蕊 2020-02-21 CN claimed
CN-110776748-A Addition type fluorosilicone rubber and preparation method thereof 宁波泰意德过滤技术有限公司 2020-02-11 CN claimed
US-5489623-A APPLYING POLYMER TO SURFACE, EXPOSING TO INCIDENT PHOTONICRADIATION TO RENDER PORTIONS LESS SOLUBLE OR DISPERSIBLE THE DOW CHEMICAL COMPANY (US) 1996-02-06 US claimed
EP-0676062-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1995-10-11 EP claimed
US-5426164-A Solvent and chemical resistant coatings and photoresists; photocuring of perfluorovinyl polymers containing photo active sites; cyclization THE DOW CHEMICAL COMPANY (US) 1995-06-20 US claimed
WO-1994015258-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1994-07-07 WO claimed
CN-113214425-B Modified polytetrafluoroethylene and preparation method and application thereof 深圳市圣一科技有限公司 2023-10-27 CN disclosed
CN-110330710-B Pressure-resistant PE pipe and preparation method thereof 福建亚通新材料科技股份有限公司 2021-10-26 CN disclosed
CN-110330710-B Pressure-resistant PE pipe and preparation method thereof 福建亚通新材料科技股份有限公司 2021-10-26 CN disclosed
CN-113214425-A Modified polytetrafluoroethylene and preparation method and application thereof 深圳市圣一科技有限公司 2021-08-06 CN disclosed
CN-110828872-B High-temperature proton exchange membrane for fuel cell and preparation method thereof 江苏擎动新能源科技有限公司 2021-03-12 CN disclosed
WO-1994015258-A1 PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS THE DOW CHEMICAL COMPANY (US) 1994-07-07 WO disclosed
US-5159038-A Flexibility, tensile strength DOW CHEMICAL COMPANY (US) 1992-10-27 US disclosed
EP-0490335-A2 Laminates of polymers having perfluorocyclobutane rings and polymers containing perfluorocyclobutane rings THE DOW CHEMICAL COMPANY (US) 1992-06-17 EP disclosed
US-5037917-A Polymerizing Monomers Containing At Least Two Perfluorovinyl Groups, Then Heating To Form Perfluorocyclobutane Rings THE DOW CHEMICAL COMPANY (US) 1991-08-06 US disclosed
EP-0428708-A1 PROCESS FOR PREPARING A POLYMER HAVING PERFLUOROCYCLOBUTANE RINGS AND POLYMERS CONTAINING PERFLUOROCYCLOBUTANE RINGS. DOW CHEMICAL CO (US) 1991-05-29 EP disclosed
WO-1990015082-A1 PROCESS FOR PREPARING A POLYMER HAVING PERFLUOROCYCLOBUTANE RINGS AND POLYMERS CONTAINING PERFLUOROCYCLOBUTANE RINGS THE DOW CHEMICAL COMPANY (US) 1990-12-13 WO disclosed