Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | DHODH | Q02127 | 15/20 | 0.52 |
| ▸ | PARP1 | P09874 | 2/20 | 0.51 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756381 | 0.92 | KDM4E (0.51) | KDM4EHPGDDHODHPARP1RIPK1 | |
| SCHEMBL28263632 | 0.90 | KDM4E (0.50) | KDM4EHPGDDHODHPARP1RIPK1 | |
| SCHEMBL15808131 | 0.88 | KDM4E (0.56) | KDM4EHPGDDHODHPARP1CHEK1 | |
| SCHEMBL12385320 | 0.87 | PARP1 (0.62) | DHODHPARP1 | |
| SCHEMBL1917467 | 0.85 | RIPK1 (0.62) | KDM4EPARP1RIPK1CHEK1 | |
| SCHEMBL6948954 | 0.84 | NPC1 (0.55) | KDM4EHPGDDHODHPARP1 | |
| SCHEMBL4260461 | 0.83 | KDM4E (0.57) | KDM4EHPGDDHODHPARP1 | |
| SCHEMBL6841606 | 0.82 | KDM4E (0.56) | KDM4EHPGDDHODHPARP1 | |
| SCHEMBL7474954 | 0.81 | KDM4E (0.52) | KDM4EHPGDDHODHPARP1 | |
| Hydrochloric Acid SCHEMBL4885974 | 0.81 | KDM4E (0.55) | KDM4EHPGDDHODHPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995001176-A1 | USE OF AN ANGIOTENSIN II ANTAGONIST AS AN OCULAR HYPOTENSIVE AGENT | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1995-01-12 | — | — | WO | disclosed |