Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 3/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7928085 | 0.81 | ALDH1A1 (0.39) | GPR3AKR1C2AKR1C1NOTUMMRGPRX4 | |
| SCHEMBL19643066 | 0.81 | ALDH1A1 (0.34) | GPR3AKR1C2AKR1C1WDR5NOTUM | |
| SCHEMBL19642956 | 0.79 | ALDH1A1 (0.33) | GPR3AKR1C2AKR1C1WDR5NOTUM | |
| SCHEMBL31680183 | 0.79 | ALDH1A1 (0.33) | GPR3AKR1C2AKR1C1WDR5NOTUM | |
| SCHEMBL1040929 | 0.79 | GPR3 (0.41) | GPR3AKR1C2AKR1C1NOTUMMRGPRX4 | |
| SCHEMBL11274922 | 0.79 | GPR3 (0.36) | GPR3AKR1C2AKR1C1NOTUMHDAC3 | |
| SCHEMBL13749060 | 0.78 | ALDH1A1 (0.38) | GPR3AKR1C2AKR1C1NOTUMPGK1 | |
| SCHEMBL29778859 | 0.78 | CA1 (0.42) | GPR3AKR1C2AKR1C1WDR5NOTUM | |
| SCHEMBL19643366 | 0.78 | CA1 (0.42) | GPR3AKR1C2AKR1C1WDR5NOTUM | |
| SCHEMBL3205177 | 0.78 | AKR1C2 (0.43) | AKR1C2AKR1C1WDR5HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380865-A | Halogen substituents | MAY & BAKER LIMITED (GB) | 1995-01-10 | — | — | US | disclosed |
| US-5206257-A | Controlling plant nematodes, helminth, protozoa | MAY & BAKER LIMITED (GB) | 1993-04-27 | — | — | US | disclosed |
| EP-0283173-A1 | Pesticidal method using 2-phenylimidazole derivatives | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1988-09-21 | — | — | EP | disclosed |