Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | ANPEP | P15144 | 2/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.49 |
| ▸ | LAP3 | P28838 | 1/20 | 0.49 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5807651 | 0.90 | OPRK1 (0.59) | OPRK1KDM4EDPP4ESR1ESR2 | |
| SCHEMBL7085691 | 0.88 | EPHX1 (0.48) | SIGMAR1ANPEPERAP1SLC6A2HTR2A | |
| SCHEMBL6181872 | 0.87 | TRPV1 (0.55) | OPRK1KDM4ETRPV1ANPEPERAP2 | |
| SCHEMBL11775728 | 0.86 | FNTA (0.54) | TRPV1SIGMAR1ESR1ESR2FNTA | |
| SCHEMBL145170 | 0.83 | TRPV1 (0.62) | OPRK1KDM4ETRPV1SIGMAR1ANPEP | |
| SCHEMBL3215341 | 0.81 | OPRK1 (0.59) | OPRK1KDM4ETRPV1SIGMAR1ESR1 | |
| SCHEMBL6675718 | 0.81 | ANPEP (0.57) | OPRK1KDM4ETRPV1SIGMAR1ANPEP | |
| SCHEMBL7547922 | 0.80 | TRPA1 (0.48) | ANPEPERAP2ERAP1ACESLC6A2 | |
| SCHEMBL7547930 | 0.80 | TRPA1 (0.48) | ANPEPERAP2ERAP1ACESLC6A2 | |
| SCHEMBL717373 | 0.79 | ESR1 (0.78) | KDM4EESR1ESR2KMT2AFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470834-A | Metalloproteinase enzyme inhibitors for arthritis, rheumatism and cancers | FLORIDA STATE UNIVERSITY (US) | 1995-11-28 | — | — | US | disclosed |