Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228476 | 0.91 | CACNA1F (0.46) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| SCHEMBL9625141 | 0.87 | THRA (0.52) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| SCHEMBL8761778 | 0.74 | KCNH2 (0.56) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| SCHEMBL9228481 | 0.73 | KCNH2 (0.47) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| SCHEMBL9625631 | 0.73 | KDM4E (0.58) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| SCHEMBL8198120 | 0.72 | KCNH2 (0.79) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| SCHEMBL8198128 | 0.72 | KCNH2 (0.79) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| SCHEMBL8198119 | 0.72 | KCNH2 (0.79) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| SCHEMBL8899350 | 0.72 | KCNH2 (0.46) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 | |
| SCHEMBL9625720 | 0.71 | CACNA1F (0.64) | CACNA1FCHRM2ADRA2BADRA2CCHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405997-A | Stable against rapid metabolism | THE UPJOHN COMPANY (US) | 1995-04-11 | — | — | US | disclosed |