Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228476 | 0.88 | CACNA1F (0.46) | THRAKDM4EPTGS2CACNA1FCHRM2 | |
| SCHEMBL9224529 | 0.87 | CACNA1F (0.43) | THRAKDM4EPTGS2CACNA1FCHRM2 | |
| SCHEMBL9625631 | 0.85 | KDM4E (0.58) | THRAKDM4EPTGS2CACNA1FCHRM2 | |
| SCHEMBL9625720 | 0.83 | CACNA1F (0.64) | THRAKDM4EPTGS2CACNA1FCHRM2 | |
| Hydrochloric Acid SCHEMBL9625546 | 0.82 | CACNA1F (0.63) | THRAKDM4EPTGS2CACNA1FCHRM2 | |
| SCHEMBL9624837 | 0.80 | CHRM2 (0.62) | THRAKDM4EPTGS2CACNA1FCHRM2 | |
| SCHEMBL9625149 | 0.79 | CACNA1F (0.50) | KDM4EPTGS2CACNA1FCHRM2ADRA2B | |
| Hydrochloric Acid SCHEMBL9624737 | 0.79 | CACNA1F (0.61) | THRAKDM4EPTGS2CACNA1FCHRM2 | |
| SCHEMBL9625076 | 0.78 | THRA (0.58) | THRAKDM4EPTGS2CACNA1FCHRM2 | |
| SCHEMBL10645163 | 0.74 | KCNH2 (0.61) | KDM4ECACNA1FCHRM2ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101412687-A | Preparation of optically-active pure ibutilide fumarate | UNIV ZHEJIANG NORMAL (CN) | 2009-04-22 | — | — | CN | claimed |
| WO-2025089725-A1 | SMOKING ARTICLE AND AEROSOL-GENERATING DEVICE USING SAME | 주식회사 이엠텍 | 2025-05-01 | — | — | WO | disclosed |
| WO-2024242252-A1 | SEMI-SOLID OR SOLID BODY FOR ELECTRONIC CIGARETTE AND METHOD FOR MANUFACTURING SAME | 주식회사 이엠텍 | 2024-11-28 | — | — | WO | disclosed |
| WO-2024232553-A1 | SOLID SUBSTANCE FOR ELECTRONIC CIGARETTE AND METHOD FOR PRODUCING SAME | 주식회사 이엠텍 | 2024-11-14 | — | — | WO | disclosed |
| CN-103664711-A | Preparation technology of ibutilide fumarate intermediate | BENGBU BBCA TUSHAN PHARM CO | 2014-03-26 | — | — | CN | disclosed |
| CN-103664711-A | Preparation technology of ibutilide fumarate intermediate | BENGBU BBCA TUSHAN PHARM CO | 2014-03-26 | — | — | CN | disclosed |
| CN-101412687-A | Preparation of optically-active pure ibutilide fumarate | UNIV ZHEJIANG NORMAL (CN) | 2009-04-22 | — | — | CN | disclosed |
| US-5155268-A | Antiarrhythmic N-aminoalkylene alkyl and aryl sulfonamides | THE UPJOHN COMPANY (US) | 1992-10-13 | — | — | US | disclosed |