SCHEMBL9224696

SCHEMBL9224696

CCCCCCCCCC(F)c1cc(OCc2ccccc2)ccc1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CTRC Q99895 1/20 0.49
MAOB P27338 1/20 0.48
PTPN11 Q06124 2/20 0.46
LTB4R Q15722 1/20 0.43
LTB4R2 Q9NPC1 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MCL1 Q07820 1/20 0.43
PLA2G2D Q9UNK4 1/20 0.43
SLC16A3 O15427 1/20 0.42
NR4A2 P43354 2/20 0.42
NR4A1 P22736 1/20 0.42
NR4A3 Q92570 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9809647 0.86 CTRC (0.47) CTRCMAOBPTPN11LTB4RLTB4R2
SCHEMBL9809646 0.86 CTRC (0.47) CTRCMAOBPTPN11LTB4RLTB4R2
SCHEMBL9224875 0.80 PPARA (0.46) ALDH1A1
SCHEMBL4819103 0.78 MAOB (0.59) MAOBLTB4RLTB4R2ALDH1A1MCL1
SCHEMBL1257328 0.78 ALDH1A1 (0.55) PTPN11ALDH1A1
SCHEMBL7909000 0.77 MAOB (0.58) MAOBPTPN11LTB4RLTB4R2ALDH1A1
SCHEMBL13965403 0.77 CTRC (0.46) CTRCMAOBPTPN11ALDH1A1MCL1
SCHEMBL22438999 0.76 PTPN11 (0.62) MAOBPTPN11MCL1
SCHEMBL22438896 0.76 PTPN11 (0.62) MAOBPTPN11MCL1
Lithium Ion SCHEMBL29695998 0.76 MAOB (0.57) MAOBLTB4RLTB4R2ALDH1A1MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0422996-B1 Liquid crystal compound SHOWA SHELL SEKIYU (JP) 1995-04-12 EP disclosed
US-5328641-A Naphthalene ester derivatives with trifluoromethyl groups SHOWA SHELL SEKIYU KABUSHIKI KAISHA 1994-07-12 US disclosed
US-5207947-A Trifluoroalkyl diaryl triesters; antiferroelectricity; electrooptics SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1993-05-04 US disclosed
EP-0422996-A2 Liquid crystal compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1991-04-17 EP disclosed