Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 5/20 | 0.33 |
| ▸ | CES1 | P23141 | 4/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218393 | 1.00 | LMNA (0.37) | LMNAMAPTDNM1TSHRTHRB | |
| SCHEMBL9223928 | 1.00 | LMNA (0.37) | LMNAMAPTDNM1TSHRTHRB | |
| SCHEMBL9870849 | 0.82 | MAPT (0.33) | LMNAMAPTDNM1TSHRTHRB | |
| SCHEMBL11282496 | 0.80 | GPR84 (0.39) | LMNAMAPTDNM1TSHRTHRB | |
| SCHEMBL9222681 | 0.79 | OPRM1 (0.33) | LMNAMAPTDNM1OPRM1CYP1A2 | |
| SCHEMBL9217810 | 0.79 | OPRM1 (0.33) | LMNAMAPTDNM1OPRM1CYP1A2 | |
| SCHEMBL9225013 | 0.79 | OPRM1 (0.33) | LMNAMAPTDNM1OPRM1CYP1A2 | |
| SCHEMBL23951461 | 0.78 | TSHR (0.50) | LMNAMAPTDNM1TSHRTHRB | |
| SCHEMBL2892345 | 0.78 | TSHR (0.50) | LMNAMAPTDNM1TSHRTHRB | |
| SCHEMBL31596116 | 0.78 | TSHR (0.50) | LMNAMAPTDNM1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118879-A | Used in the synthesis of medicinal and agricultural chemicals and water- and oil-repellent agents | NIPPON OIL AND FATS CO., LTD. (JP) | 1992-06-02 | — | — | US | claimed |
| EP-0420987-A1 | Process for preparing fluoroalkyl derivatives | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1991-04-10 | — | — | EP | claimed |
| EP-0420987-B1 | Process for preparing fluoroalkyl derivatives | NIPPON OILS & FATS CO LTD (JP) | 1995-05-03 | — | — | EP | disclosed |
| US-5118879-A | Used in the synthesis of medicinal and agricultural chemicals and water- and oil-repellent agents | NIPPON OIL AND FATS CO., LTD. (JP) | 1992-06-02 | — | — | US | disclosed |
| EP-0420987-A1 | Process for preparing fluoroalkyl derivatives | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1991-04-10 | — | — | EP | disclosed |