SCHEMBL9870849

SCHEMBL9870849

CCCCCCCCC(Cl)CC(F)(Cl)C(F)(F)Cl

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.33
LMNA P02545 1/20 0.33
DNM1 Q05193 2/20 0.32
OPRM1 P35372 1/20 0.31
FDPS P14324 2/20 0.31
TSHR P16473 1/20 0.31
THRB P10828 1/20 0.31
FAAH O00519 5/20 0.31
CES1 P23141 4/20 0.31
GPR84 Q9NQS5 2/20 0.31
CES2 O00748 1/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9218393 0.82 LMNA (0.37) MAPTLMNADNM1OPRM1FDPS
SCHEMBL9223928 0.82 LMNA (0.37) MAPTLMNADNM1OPRM1FDPS
SCHEMBL9224924 0.82 LMNA (0.37) MAPTLMNADNM1OPRM1FDPS
SCHEMBL11282496 0.79 GPR84 (0.39) MAPTLMNADNM1OPRM1FDPS
SCHEMBL9222681 0.74 OPRM1 (0.33) MAPTLMNADNM1OPRM1CYP1A2
SCHEMBL9217810 0.74 OPRM1 (0.33) MAPTLMNADNM1OPRM1CYP1A2
SCHEMBL9225013 0.74 OPRM1 (0.33) MAPTLMNADNM1OPRM1CYP1A2
SCHEMBL9580466 0.74 DNM1 (0.31) DNM1
SCHEMBL23951461 0.73 TSHR (0.50) MAPTLMNADNM1OPRM1FDPS
SCHEMBL18722590 0.73 TSHR (0.50) MAPTLMNADNM1OPRM1FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4997855-A Nematocides, insecticides, anthelmintics FMC CORPORATION (US) 1991-03-05 US disclosed
US-4876285-A ANTHELMINTIC UTILITY FMC CORPORATION (US) 1989-10-24 US disclosed
US-4603147-A Biocidal fluoroalkanes and fluoroalkenes FMC CORPORATION (US) 1986-07-29 US disclosed
EP-0164404-A1 BIOCIDAL FLUOROALKANES AND FLUOROALKENES FMC Corporation (US) 1985-12-18 EP disclosed
WO-1985002519-A1 BIOCIDAL FLUOROALKANES AND FLUOROALKENES FMC CORPORATION (US) 1985-06-20 WO disclosed