Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29350914 | 1.00 | MAPT (0.47) | MAPTCYP1A2CYP2C9CYP2C19ADRA1D | |
| SCHEMBL29834220 | 0.84 | MAPT (0.67) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL29496547 | 0.84 | MAPT (0.67) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL1606348 | 0.84 | MAPT (0.67) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL3274613 | 0.83 | MAPT (0.62) | MAPTCYP1A2CYP2C9CYP2C19ADRA1D | |
| SCHEMBL146878 | 0.82 | ALDH1A1 (0.44) | MAPTCYP1A2WDR5 | |
| SCHEMBL5107 | 0.82 | ALDH1A1 (0.44) | MAPTCYP1A2WDR5 | |
| SCHEMBL29350037 | 0.82 | ALDH1A1 (0.44) | MAPTCYP1A2WDR5 | |
| SCHEMBL29496111 | 0.82 | ALDH1A1 (0.44) | MAPTCYP1A2WDR5 | |
| SCHEMBL10323632 | 0.82 | ALDH1A1 (0.44) | MAPTCYP1A2WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220081413-A1 | SYNTHESIS OF QUINAZOLINE COMPOUNDS | GENENTECH, INC. (US) | 2022-03-17 | — | — | US | disclosed |
| EP-0503884-B1 | Optically active diphenylphosphino-binaphtyl compounds and catalytic transition metal complexes thereof | TAKASAGO PERFUMERY CO LTD (JP) | 1995-07-26 | — | — | EP | disclosed |
| US-5231202-A | OPTICALLY ACTIVE TERTIARY PHOSPHINE COMPOUND AND TRANSITION METAL COMPLEX USING THE SAME AS LIGAND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1993-07-27 | — | — | US | disclosed |
| EP-0503884-A1 | Optically active diphenylphosphino-binaphtyl compounds and catalytic transition metal complexes thereof | Takasago International Corporation (JP) | 1992-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220081413-A1 | SYNTHESIS OF QUINAZOLINE COMPOUNDS | COQ8A, SQSTM1, QARS1 | MAPT 650/4885CYP1A2 89/4885CYP2C9 256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.