Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9225590 | 0.89 | MEN1 (0.40) | MMP2MMP3MMP9ALDH1A1 | |
| SCHEMBL9222752 | 0.85 | MMP1 (0.40) | MMP2MMP3MMP9MMP8MMP13 | |
| SCHEMBL9226552 | 0.83 | MEN1 (0.40) | MMP2MMP3MMP9ALDH1A1 | |
| SCHEMBL9221905 | 0.83 | CHRNA7 (0.34) | MMP2MMP3MMP9PPARAALDH1A1 | |
| SCHEMBL9228212 | 0.82 | CNR2 (0.36) | — | |
| SCHEMBL9225864 | 0.81 | GRIA4 (0.40) | HDAC3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9224130 | 0.81 | ATM (0.34) | — | |
| SCHEMBL9227289 | 0.81 | FAAH (0.34) | MMP2ALDH1A1LMNA | |
| SCHEMBL9227287 | 0.80 | HTR2A (0.44) | ALDH1A1LMNA | |
| SCHEMBL9225116 | 0.76 | CNR2 (0.40) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590020-B1 | CURABLE ORGANOPOLYSILOXANE PREPARATIONS | WACKER CHEMIE GMBH (DE) | 1995-09-06 | — | — | EP | disclosed |
| US-5420222-A | Curable organo(poly)siloxane compositions | WACKER-CHEMIE GMBH (DE) | 1995-05-30 | — | — | US | disclosed |
| EP-0590020-A1 | CURABLE ORGANOPOLYSILOXANE PREPARATIONS. | WAKKER CHEMIE GMBH (DE) | 1994-04-06 | — | — | EP | disclosed |
| WO-1993000405-A1 | CURABLE ORGANOPOLYSILOXANE PREPARATIONS | WACKER-CHEMIE GMBH (DE) | 1993-01-07 | — | — | WO | disclosed |