Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9225590 | 0.94 | MEN1 (0.40) | MEN1KMT2ANAAAPOLBMMP2 | |
| SCHEMBL9225632 | 0.83 | LTA4H (0.47) | MMP2MMP9MMP3ALDH1A1 | |
| SCHEMBL9226954 | 0.83 | MEN1 (0.42) | MEN1KMT2ANAAAPOLBATM | |
| SCHEMBL9221905 | 0.82 | CHRNA7 (0.34) | MEN1KMT2ANAAAMMP2MMP9 | |
| SCHEMBL9228212 | 0.80 | CNR2 (0.36) | — | |
| SCHEMBL9225864 | 0.79 | GRIA4 (0.40) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9224130 | 0.79 | ATM (0.34) | MEN1KMT2AATMHTR2AMAPK1 | |
| SCHEMBL9227289 | 0.79 | FAAH (0.34) | MMP2ALDH1A1 | |
| SCHEMBL9227287 | 0.78 | HTR2A (0.44) | HTR2AALDH1A1 | |
| SCHEMBL9222752 | 0.78 | MMP1 (0.40) | MEN1KMT2AMMP2MMP9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590020-B1 | CURABLE ORGANOPOLYSILOXANE PREPARATIONS | WACKER CHEMIE GMBH (DE) | 1995-09-06 | — | — | EP | disclosed |
| US-5420222-A | Curable organo(poly)siloxane compositions | WACKER-CHEMIE GMBH (DE) | 1995-05-30 | — | — | US | disclosed |
| EP-0590020-A1 | CURABLE ORGANOPOLYSILOXANE PREPARATIONS. | WAKKER CHEMIE GMBH (DE) | 1994-04-06 | — | — | EP | disclosed |
| WO-1993000405-A1 | CURABLE ORGANOPOLYSILOXANE PREPARATIONS | WACKER-CHEMIE GMBH (DE) | 1993-01-07 | — | — | WO | disclosed |