Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | STS | P08842 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228212 | 0.87 | CNR2 (0.36) | CNR2SLC2A1CNR1NR1I2 | |
| SCHEMBL9224130 | 0.85 | ATM (0.34) | STSMEN1KMT2ASLC2A1NR1I2 | |
| SCHEMBL9227289 | 0.85 | FAAH (0.34) | ALDH1A1LMNASLC2A1NR1I2 | |
| SCHEMBL9225590 | 0.85 | MEN1 (0.40) | MEN1ALDH1A1KMT2A | |
| SCHEMBL9227287 | 0.84 | HTR2A (0.44) | STSALDH1A1LMNAHSD17B10 | |
| SCHEMBL9222752 | 0.84 | MMP1 (0.40) | MEN1MAPTKMT2ACNR2SLC2A1 | |
| SCHEMBL9225632 | 0.81 | LTA4H (0.47) | HDAC3ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9225116 | 0.80 | CNR2 (0.40) | CNR2LMNACNR1NR1I2 | |
| SCHEMBL9221905 | 0.80 | CHRNA7 (0.34) | MEN1ALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL9226552 | 0.79 | MEN1 (0.40) | MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590020-B1 | CURABLE ORGANOPOLYSILOXANE PREPARATIONS | WACKER CHEMIE GMBH (DE) | 1995-09-06 | — | — | EP | disclosed |
| US-5420222-A | Curable organo(poly)siloxane compositions | WACKER-CHEMIE GMBH (DE) | 1995-05-30 | — | — | US | disclosed |
| EP-0590020-A1 | CURABLE ORGANOPOLYSILOXANE PREPARATIONS. | WAKKER CHEMIE GMBH (DE) | 1994-04-06 | — | — | EP | disclosed |
| WO-1993000405-A1 | CURABLE ORGANOPOLYSILOXANE PREPARATIONS | WACKER-CHEMIE GMBH (DE) | 1993-01-07 | — | — | WO | disclosed |