SCHEMBL92264

SCHEMBL92264

O=C(OO)c1ccc2c(=O)[nH]sc2c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.60
LMNA P02545 3/20 0.60
ALDH1A1 P00352 3/20 0.60
POLB P06746 1/20 0.60
KDM4E B2RXH2 3/20 0.44
HTT P42858 2/20 0.44
DDAH1 O94760 1/20 0.44
CASP3 P42574 1/20 0.44
CACNA1B Q00975 1/20 0.44
APBA1 Q02410 1/20 0.44
MAOA P21397 1/20 0.42
PARP1 P09874 7/20 0.39
MAP2K4 P45985 1/20 0.33
HPGD P15428 2/20 0.32
CSNK2A1 P68400 2/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
TNF P01375 1/20 0.32
GAA P10253 1/20 0.32
NR2F2 P24468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6232500 0.86 ALDH1A1 (0.50) MAPTLMNAALDH1A1POLBKDM4E
SCHEMBL6152844 0.81 ALDH1A1 (0.56) MAPTLMNAALDH1A1POLBKDM4E
SCHEMBL25834539 0.75 ALDH1A1 (0.53) MAPTLMNAALDH1A1POLBKDM4E
SCHEMBL81346 0.72 ALDH1A1 (0.61) MAPTLMNAALDH1A1POLBKDM4E
SCHEMBL79178 0.71 MAPT (0.51) MAPTLMNAALDH1A1POLBKDM4E
SCHEMBL1286650 0.70 CES2 (0.48) MAPTLMNAALDH1A1HTTKMT2A
SCHEMBL13455388 0.68 ALDH1A1 (0.61) MAPTLMNAALDH1A1POLBKDM4E
SCHEMBL5807922 0.68 ALDH1A1 (0.61) MAPTLMNAALDH1A1POLBKDM4E
SCHEMBL11737600 0.68 ALDH1A1 (0.61) MAPTLMNAALDH1A1POLBKDM4E
Ticlatone SCHEMBL193888 0.68 ALDH1A1 (0.61) MAPTLMNAALDH1A1POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129308-B2 Thermal transfer image-receiving sheet and surface condition improver FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-20090087552-A1 METHOD OF PRODUCING HEAT-SENSITIVE TRANSFER IMAGE-RECEIVING SHEET FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090011154-A1 THERMAL TRANSFER IMAGE-RECEIVING SHEET AND SURFACE CONDITION IMPROVER FUJIFILM CORPORATION (JP) 2009-01-08 US disclosed