SCHEMBL79178

SCHEMBL79178

O=c1[nH]sc2cc(OC(O)O)ccc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.51
ALDH1A1 P00352 2/20 0.51
LMNA P02545 2/20 0.51
POLB P06746 1/20 0.51
HTT P42858 2/20 0.44
KDM4E B2RXH2 2/20 0.44
DDAH1 O94760 1/20 0.44
CASP3 P42574 1/20 0.44
CACNA1B Q00975 1/20 0.44
APBA1 Q02410 1/20 0.44
MAOA P21397 1/20 0.42
PARP15 Q460N3 2/20 0.35
PARP10 Q53GL7 2/20 0.35
TNKS2 Q9H2K2 2/20 0.35
PARP2 Q9UGN5 2/20 0.35
MPI P34949 1/20 0.31
PRNP P04156 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
PPARG P37231 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9827851 0.84 LMNA (0.56) MAPTALDH1A1LMNAPOLBHTT
SCHEMBL6228576 0.78 MAOA (0.59) MAPTALDH1A1LMNAPOLBHTT
SCHEMBL78785 0.74 ALDH1A1 (0.53) MAPTALDH1A1LMNAPOLBHTT
SCHEMBL92264 0.71 MAPT (0.60) MAPTALDH1A1LMNAPOLBHTT
SCHEMBL6232500 0.70 ALDH1A1 (0.50) MAPTALDH1A1LMNAPOLBHTT
SCHEMBL20463095 0.69 ALDH1A1 (0.45) MAPTALDH1A1LMNAPOLBHTT
SCHEMBL5807922 0.68 ALDH1A1 (0.61) MAPTALDH1A1LMNAPOLBHTT
Ticlatone SCHEMBL30165586 0.68 ALDH1A1 (0.61) MAPTALDH1A1LMNAPOLBHTT
SCHEMBL11737600 0.68 ALDH1A1 (0.61) MAPTALDH1A1LMNAPOLBHTT
SCHEMBL8130952 0.68 ALDH1A1 (1.00) MAPTALDH1A1LMNAPOLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129308-B2 Thermal transfer image-receiving sheet and surface condition improver FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-20090087552-A1 METHOD OF PRODUCING HEAT-SENSITIVE TRANSFER IMAGE-RECEIVING SHEET FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
EP-2042334-A2 Method of producing heat-sensitive transfer image-receiving sheet Fujifilm Corporation (JP) 2009-04-01 EP disclosed
US-20090011154-A1 THERMAL TRANSFER IMAGE-RECEIVING SHEET AND SURFACE CONDITION IMPROVER FUJIFILM CORPORATION (JP) 2009-01-08 US disclosed
EP-1974946-A1 Thermal transfer image-receiving sheet and surface condition improver FUJIFILM Corporation (JP) 2008-10-01 EP disclosed