SCHEMBL922753

SCHEMBL922753

CCC(C)Cc1ccccc1Oc1ccc(CNC(=O)c2ccc(C)nc2N)cc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 3/20 0.43
PRMT6 Q96LA8 3/20 0.43
PPARA Q07869 6/20 0.42
PPARG P37231 4/20 0.42
PPARD Q03181 2/20 0.42
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
GAA P10253 1/20 0.41
HTT P42858 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAPK14 Q16539 2/20 0.41
EPHX2 P34913 1/20 0.41
MAPK1 P28482 3/20 0.40
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38
KDM4E B2RXH2 1/20 0.38
GALR3 O60755 1/20 0.38
NR2F2 P24468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920821 0.92 CARM1 (0.45) CARM1PRMT6PPARAPPARGPPARD
SCHEMBL920616 0.90 PPARA (0.43) CARM1PRMT6PPARAPPARGPPARD
SCHEMBL920517 0.90 ALDH1A1 (0.47) CARM1PRMT6ALDH1A1HPGDGAA
SCHEMBL921168 0.88 PPARA (0.42) CARM1PRMT6PPARAPPARGPPARD
SCHEMBL921360 0.88 PPARG (0.45) PPARAPPARGPPARDHTTMAPK14
SCHEMBL921228 0.87 ALDH1A1 (0.47) CARM1PRMT6PPARAALDH1A1HPGD
SCHEMBL922806 0.86 CARM1 (0.43) CARM1PRMT6ALDH1A1HPGDGAA
SCHEMBL920693 0.86 MAPK8 (0.47) CARM1PRMT6PPARAPPARGPPARD
SCHEMBL920231 0.85 ALDH1A1 (0.45) CARM1PRMT6ALDH1A1HPGDGAA
SCHEMBL919878 0.84 ALDH1A1 (0.44) CARM1PRMT6ALDH1A1HPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 CARM1 273/4885PRMT6 1994/4885PPARA 494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.