SCHEMBL921168

SCHEMBL921168

CCC(C)Cc1ccccc1Oc1ccc(CNC(=O)c2ccc(COC)nc2N)cc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 11/20 0.42
PPARG P37231 6/20 0.42
PPARD Q03181 3/20 0.42
CARM1 Q86X55 2/20 0.41
PRMT6 Q96LA8 2/20 0.41
ALDH1A1 P00352 2/20 0.39
GAA P10253 2/20 0.39
HPGD P15428 2/20 0.39
HTT P42858 2/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
EPHX2 P34913 1/20 0.38
PKM P14618 1/20 0.37
MAPK14 Q16539 1/20 0.37
RORC P51449 1/20 0.37
RXFP1 Q9HBX9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL919648 0.92 CARM1 (0.43) PPARAPPARGPPARDCARM1PRMT6
SCHEMBL922047 0.90 HPGD (0.43) PPARAPPARGPPARDCARM1PRMT6
SCHEMBL922979 0.89 PPARA (0.42) PPARAPPARGPPARDALDH1A1HPGD
SCHEMBL921327 0.88 HPGD (0.44) PPARAPPARGPPARDCARM1PRMT6
SCHEMBL922753 0.88 CARM1 (0.43) PPARAPPARGPPARDCARM1PRMT6
SCHEMBL921797 0.87 CARM1 (0.42) PPARAPPARGPPARDCARM1PRMT6
SCHEMBL920616 0.87 PPARA (0.43) PPARAPPARGPPARDCARM1PRMT6
SCHEMBL919238 0.86 ALDH1A1 (0.42) PPARAPPARGPPARDCARM1PRMT6
SCHEMBL920440 0.86 PPARA (0.42) PPARAPPARGPPARDCARM1PRMT6
SCHEMBL921334 0.85 ALDH1A1 (0.42) PPARAPPARGPPARDCARM1PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 PPARA 494/4885PPARG 391/4885PPARD 360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.