Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.66 |
| ▸ | CTSK | P43235 | 7/20 | 0.66 |
| ▸ | CTSL | P07711 | 4/20 | 0.66 |
| ▸ | CTSB | P07858 | 4/20 | 0.66 |
| ▸ | AKT1 | P31749 | 1/20 | 0.62 |
| ▸ | SYK | P43405 | 1/20 | 0.60 |
| ▸ | TACR1 | P25103 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14598326 | 0.91 | CTSS (0.65) | CTSSCTSKCTSLCTSBAKT1 | |
| SCHEMBL14598339 | 0.91 | CTSS (0.65) | CTSSCTSKCTSLCTSBAKT1 | |
| SCHEMBL21010315 | 0.89 | CTSS (0.79) | CTSSCTSKCTSLCTSBAKT1 | |
| SCHEMBL2440946 | 0.89 | CTSS (0.79) | CTSSCTSKCTSLCTSBAKT1 | |
| SCHEMBL17643540 | 0.89 | CTSL (0.76) | CTSSCTSKCTSLCTSBTACR1 | |
| SCHEMBL14485661 | 0.89 | CTSS (0.64) | CTSSCTSKCTSLCTSBAKT1 | |
| SCHEMBL20136152 | 0.89 | CTSS (0.64) | CTSSCTSKCTSLCTSBAKT1 | |
| SCHEMBL4857149 | 0.88 | MAPT (0.58) | CTSSCTSKCTSLCTSBSYK | |
| SCHEMBL9227553 | 0.88 | SYK (0.62) | CTSSCTSKCTSLCTSBAKT1 | |
| SCHEMBL4229789 | 0.87 | TACR1 (0.68) | CTSSCTSKCTSLCTSBSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872850-B2 | Small molecule inhibitors of secretion of proteins encoded by ARE-mRNAs | MESSAGE PHARMACEUTICALS (US) | 2005-03-29 | — | — | US | disclosed |
| WO-2002083842-A9 | SMALL MOLECULE INHIBITORS OF SECRETION OF PROTEINS ENCODED BY ARE-MRNAS | MESSAGE PHARMACEUTICALS INC (US) | 2004-04-29 | — | — | WO | disclosed |
| US-20030199453-A1 | Small molecule inhibitors of secretion of proteins encoded by ARE-mRNAs | S. R. ONE, LIMITED | 2003-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199453-A1 | Small molecule inhibitors of secretion of proteins encoded by ARE-mRNAs | ASF1A, IGF2BP1, SERBP1 | CTSS 1508/4885CTSK 2860/4885CTSL 2876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.