SCHEMBL9228181

SCHEMBL9228181

N#CCCC(CCC#N)(CCC#N)O[SiH3]

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
LOX P28300 1/20 0.30
LOXL3 P58215 1/20 0.30
LOXL2 Q9Y4K0 1/20 0.30
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1224721 0.74
SCHEMBL5682726 0.74
SCHEMBL6747548 0.72 TSHR (0.41) MEN1KMT2ATSHR
SCHEMBL25728898 0.70 ALDH1A1 (0.35) ALDH1A1TDP1MEN1KMT2A
SCHEMBL24720886 0.65 ALDH1A1 (0.50) ALDH1A1TDP1MEN1KMT2ALOX
SCHEMBL17935652 0.65 ALDH1A1 (0.50) ALDH1A1TDP1MEN1KMT2ALOX
SCHEMBL1225264 0.65 TSHR (0.33) ALDH1A1TDP1CYP3A4TSHR
SCHEMBL235279 0.65 TSHR (0.39) ALDH1A1TDP1MEN1KMT2ATSHR
SCHEMBL2864686 0.65 TSHR (0.39) ALDH1A1TDP1MEN1KMT2ATSHR
SCHEMBL1224436 0.65 CYP3A4 (0.31) ALDH1A1TDP1MEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0682034-A2 Process for organooxylation of cyanoalkylchlorosilanes DOW CORNING CORPORATION (US) 1995-11-15 EP disclosed
US-5374757-A Alcoholic esterification of silicon atom to form B-cyanoalkyl-organooxysilane; using falling-film or wiped-film type reactor DOW CORNING CORPORATION (US) 1994-12-20 US disclosed