Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3482566 | 0.75 | TSHR (0.35) | TSHR | |
| SCHEMBL3481794 | 0.75 | LMNA (0.30) | TSHR | |
| SCHEMBL235279 | 0.74 | TSHR (0.39) | TSHRMEN1KMT2A | |
| SCHEMBL23930358 | 0.73 | TSHR (0.40) | TSHR | |
| SCHEMBL6303628 | 0.73 | TSHR (0.40) | TSHR | |
| SCHEMBL28431829 | 0.73 | TSHR (0.40) | TSHR | |
| SCHEMBL29012022 | 0.73 | TSHR (0.40) | TSHR | |
| SCHEMBL9228181 | 0.72 | ALDH1A1 (0.37) | TSHRMEN1KMT2A | |
| SCHEMBL15005053 | 0.71 | — | — | |
| SCHEMBL8376029 | 0.71 | TSHR (0.36) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699956-B2 | ORGANOPOLYSILOXANE CONTAINING A CYANOALKYL GROUP AND A MONOVALENT HYDROCARBON GROUP HAVING AN ALIPHATIC UNSATURATED BOND, ORGANOHYDROGENPOLYSILOXANE CONTAINING A CYANOALKYL GROUP, PLATINUM GROUP METAL CATALYST | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| US-20020198319-A1 | Highly dielectric addition type curable compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-12-26 | — | — | US | disclosed |