Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | PPIB | P23284 | 1/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | PPID | Q08752 | 1/20 | 0.42 |
| ▸ | PPIG | Q13427 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11109783 | 0.93 | CTDSP1 (0.49) | LMNACYP3A4MAOACYP1A2ALDH1A1 | |
| SCHEMBL10790625 | 0.87 | LMNA (0.53) | LMNACYP3A4MAOACYP1A2ALDH1A1 | |
| SCHEMBL11444462 | 0.84 | LMNA (0.59) | LMNACYP3A4MAOACYP1A2ALDH1A1 | |
| SCHEMBL11142995 | 0.81 | ALDH1A1 (0.51) | LMNACYP3A4CYP1A2ALDH1A1TSHR | |
| SCHEMBL1363531 | 0.81 | L3MBTL1 (0.55) | LMNACYP1A2ALDH1A1TSHRTDP1 | |
| SCHEMBL29023046 | 0.80 | LMNA (0.49) | LMNACYP3A4MAOACYP1A2ALDH1A1 | |
| SCHEMBL31147823 | 0.79 | L3MBTL1 (0.53) | LMNACYP1A2ALDH1A1TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL27606948 | 0.79 | L3MBTL1 (0.53) | LMNACYP1A2ALDH1A1TSHRTDP1 | |
| SCHEMBL27480292 | 0.79 | PTGIR (0.58) | LMNACYP1A2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL6740971 | 0.78 | CYP3A4 (0.54) | LMNACYP3A4CYP1A2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671425-A1 | Process for the preparation of highly elastic flexibel polyurethane foams | BASF Schwarzheide GmbH (DE) | 1995-09-13 | — | — | EP | claimed |
| EP-0205815-B1 | USE OF AN ANTITHROMBOGENIC SYNTHETIC ELASTOMER AND PROCESS OF PREPARATION THEREOF | Research Development Corporation of Japan (JP) | 1991-07-17 | — | — | EP | disclosed |
| US-4687831-A | Antithrombogenic synthetic elastomer and process of preparation thereof | RESEARCH DEVELOPMENT CORP. OF JAPAN (JP) | 1987-08-18 | — | — | US | disclosed |
| EP-0205815-A1 | Use of an antithrombogenic synthetic elastomer and process of preparation thereof | Research Development Corporation of Japan (JP) | 1986-12-30 | — | — | EP | disclosed |