Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 16/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867348 | 0.89 | SUV39H2 (0.43) | SUV39H2HDAC1 | |
| SCHEMBL9234782 | 0.89 | HPGDS (0.40) | SUV39H2HDAC1NAMPTGPR119 | |
| SCHEMBL9238827 | 0.82 | SUV39H2 (0.45) | SUV39H2CHRM4 | |
| SCHEMBL8867482 | 0.81 | SUV39H2 (0.47) | SUV39H2HDAC1 | |
| SCHEMBL8866643 | 0.81 | SUV39H2 (0.47) | SUV39H2HDAC1NAMPT | |
| SCHEMBL9235439 | 0.81 | SUV39H2 (0.43) | SUV39H2CHRM4 | |
| SCHEMBL9233170 | 0.81 | SUV39H2 (0.43) | SUV39H2CHRM4 | |
| Water SCHEMBL9282757 | 0.80 | SUV39H2 (0.42) | SUV39H2CHRM4 | |
| Water SCHEMBL9283601 | 0.79 | GPR119 (0.41) | SUV39H2GPR119 | |
| SCHEMBL9283018 | 0.79 | GPR119 (0.41) | SUV39H2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668278-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1995-08-23 | — | — | EP | disclosed |