SCHEMBL9229798

SCHEMBL9229798

CC(C)CNS(=O)(=O)c1ccccc1C(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
ATM Q13315 1/20 0.43
ALOX5AP P20292 3/20 0.43
FEN1 P39748 3/20 0.43
L3MBTL1 Q9Y468 1/20 0.42
GBA1 P04062 1/20 0.41
BRD4 O60885 1/20 0.40
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.40
MEN1 O00255 1/20 0.40
TSHR P16473 1/20 0.40
KMT2A Q03164 1/20 0.40
PDK1 Q15118 1/20 0.39
PDK2 Q15119 1/20 0.39
PDK3 Q15120 1/20 0.39
PDK4 Q16654 1/20 0.39
POLB P06746 1/20 0.39
OPRM1 P35372 1/20 0.39
OPRK1 P41145 1/20 0.39
HSD11B1 P28845 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9231102 0.84 CA12 (0.44) ALDH1A1ALOX5APFEN1L3MBTL1POLB
SCHEMBL9229015 0.81 CA12 (0.56) ALDH1A1L3MBTL1BRD4HPGDMEN1
SCHEMBL15352816 0.81 PKM (0.49) ALDH1A1ATMALOX5APFEN1L3MBTL1
SCHEMBL2227866 0.79 RECQL (0.56) ALDH1A1ATMALOX5APFEN1POLB
SCHEMBL15621005 0.79 GBA1 (0.63) ALDH1A1ATMALOX5APFEN1GBA1
SCHEMBL2527735 0.79 ATM (0.54) ALDH1A1ATML3MBTL1GAAMEN1
SCHEMBL5191929 0.79 CA12 (0.58) ALDH1A1L3MBTL1BRD4HPGDMEN1
SCHEMBL9230550 0.78 L3MBTL1 (0.47) ALDH1A1L3MBTL1TSHRPOLBHSD11B1
SCHEMBL2801003 0.77 ALDH1A1 (0.44) ALDH1A1ATMALOX5APFEN1GBA1
SCHEMBL21465864 0.77 CA12 (0.52) ALDH1A1ATMALOX5APFEN1GBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5437690-A Using an n-alkyl aromatic sulfonamide as dye promoter in dyeing aromatic polyamides, polybenzimidazoles, polyimides SPRINGS INDUSTRIES, INC. (US) 1995-08-01 US claimed
US-5437690-A Using an n-alkyl aromatic sulfonamide as dye promoter in dyeing aromatic polyamides, polybenzimidazoles, polyimides SPRINGS INDUSTRIES, INC. (US) 1995-08-01 US disclosed