SCHEMBL9229015

SCHEMBL9229015

CCCNS(=O)(=O)c1ccccc1C(C)C

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.56
CA9 Q16790 4/20 0.56
RECQL P46063 1/20 0.48
L3MBTL1 Q9Y468 3/20 0.45
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
POLB P06746 2/20 0.43
MEN1 O00255 1/20 0.40
TP53 P04637 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
CYP2C19 P33261 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
BRD4 O60885 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5191929 0.90 CA12 (0.58) CA12CA9RECQLL3MBTL1POLB
SCHEMBL9231102 0.86 CA12 (0.44) CA12CA9RECQLL3MBTL1POLB
SCHEMBL9229798 0.81 ALDH1A1 (0.46) L3MBTL1POLBMEN1TSHRKMT2A
SCHEMBL4616179 0.78 RAB9A (0.53) MEN1CYP1A2CYP2C19KMT2ATDP1
SCHEMBL32664495 0.77 CA12 (0.61) CA12CA9RECQLL3MBTL1CA1
SCHEMBL634315 0.77 CA12 (0.61) CA12CA9RECQLL3MBTL1CA1
SCHEMBL9230550 0.77 L3MBTL1 (0.47) CA12CA9L3MBTL1CA1CA2
SCHEMBL3555918 0.76 CA12 (0.59) CA12CA9RECQLL3MBTL1CA1
SCHEMBL21089221 0.76 RECQL (0.77) CA12CA9RECQLL3MBTL1CA1
SCHEMBL375546 0.76 CA9 (0.59) CA12CA9RECQLL3MBTL1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5437690-A Using an n-alkyl aromatic sulfonamide as dye promoter in dyeing aromatic polyamides, polybenzimidazoles, polyimides SPRINGS INDUSTRIES, INC. (US) 1995-08-01 US claimed
US-5437690-A Using an n-alkyl aromatic sulfonamide as dye promoter in dyeing aromatic polyamides, polybenzimidazoles, polyimides SPRINGS INDUSTRIES, INC. (US) 1995-08-01 US disclosed