Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.65 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL995202 | 0.91 | ACHE (0.71) | ACHEKAT6ATSHRALDH1A1ALOX15 | |
| O-Xylene SCHEMBL11776221 | 0.84 | TSHR (0.56) | ACHETSHRALDH1A1CES2CES1 | |
| SCHEMBL5065262 | 0.84 | ALDH1A1 (0.46) | ACHETSHRALDH1A1ALOX15LMNA | |
| SCHEMBL29488781 | 0.81 | — | — | |
| SCHEMBL11837 | 0.81 | — | — | |
| Formaldehyde SCHEMBL27341516 | 0.79 | ACHE (0.83) | ACHEKAT6ATSHRALDH1A1LMNA | |
| SCHEMBL28019040 | 0.79 | ACHE (0.83) | ACHETSHRALDH1A1ALOX15GAA | |
| SCHEMBL28557764 | 0.79 | ACHE (0.83) | ACHEKAT6ATSHRALDH1A1LMNA | |
| SCHEMBL29176814 | 0.78 | — | — | |
| Fluoride SCHEMBL21816907 | 0.78 | ACHE (0.94) | ACHETSHRALDH1A1GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643060-A2 | Sulfonylbenzyl-substituted benzimidazoles, process for their preparation, and their pharmaceutical use | BAYER AG (DE) | 1995-03-15 | — | — | EP | disclosed |
| EP-0564788-A2 | Sulfonylbenzyl substituted imidazopyridines as AII-antagonists | BAYER AG (DE) | 1993-10-13 | — | — | EP | disclosed |
| EP-0562261-A2 | Sulphonylbenzyl substituted imidazoles | BAYER AG (DE) | 1993-09-29 | — | — | EP | disclosed |
| EP-0557843-A2 | Sulfonylbenzyl-substituted pyridones as pharmaceuticals | BAYER AG (DE) | 1993-09-01 | — | — | EP | disclosed |
| EP-0557842-A2 | Sulphonylbenzyl substituted imidazolylpropenic acid derivatives | BAYER AG (DE) | 1993-09-01 | — | — | EP | disclosed |