Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.35 |
| ▸ | PPARD | Q03181 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335927 | 0.79 | PTGDR2 (0.39) | PTGDR2ITGB3ITGA2BPPARDPPARG | |
| SCHEMBL7399322 | 0.70 | ITGB3 (0.46) | ITGB3ITGA2B | |
| SCHEMBL7401716 | 0.69 | ITGB3 (0.50) | ITGB3ITGA2BTSHRALDH1A1 | |
| SCHEMBL8888301 | 0.68 | ITGB3 (0.45) | ITGB3ITGA2BF10HTR1AHTR2A | |
| SCHEMBL7334526 | 0.67 | ITGB3 (0.40) | ITGB3ITGA2BPPARDITGAVKDM4E | |
| SCHEMBL8630666 | 0.64 | ITGB3 (0.42) | ITGB3ITGA2BSPHK1TSHRF10 | |
| Hydrochloric Acid SCHEMBL9080887 | 0.62 | ITGB3 (0.58) | ITGB3ITGA2BTSHRALDH1A1MAPT | |
| SCHEMBL8634522 | 0.62 | HRH3 (0.47) | ITGB3ITGA2BTSHRHSD17B10KDM4E | |
| SCHEMBL7335413 | 0.62 | ITGB3 (0.52) | ITGB3ITGA2B | |
| SCHEMBL7402638 | 0.62 | ALDH1A1 (0.51) | ITGB3ITGA2BKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556977-A | ANTIAGGLOMERANTS FOR CELLS, ANTICOAGULANTS, ANTIISCHEMIC AGENTS USING PYRIDINYLPIPERAZINE DERIVATIVES | ZENECA LIMITED (GB) | 1996-09-17 | — | — | US | disclosed |