Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.40 |
| ▸ | REN | P00797 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PEPD | P12955 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8814660 | 0.84 | L3MBTL1 (0.40) | ACERENLMNAHSD17B10CYP2C19 | |
| SCHEMBL10906984 | 0.82 | ACE (0.41) | ACERENLMNAHSD17B10CYP2C19 | |
| SCHEMBL3924487 | 0.76 | ACE (0.41) | ACERENLMNAHSD17B10CYP2C19 | |
| SCHEMBL28261258 | 0.76 | ACE (0.41) | ACERENLMNAHSD17B10CYP2C19 | |
| SCHEMBL28267035 | 0.72 | ACE (0.43) | ACERENLMNAHSD17B10CYP2C19 | |
| SCHEMBL6535156 | 0.72 | LMNA (0.43) | ACERENLMNAHSD17B10CYP2C19 | |
| SCHEMBL15129898 | 0.69 | DPP4 (0.32) | — | |
| SCHEMBL151570 | 0.68 | ALDH1A1 (0.47) | ACERENLMNAHSD17B10CYP2C19 | |
| SCHEMBL151569 | 0.68 | ALDH1A1 (0.47) | ACERENLMNAHSD17B10CYP2C19 | |
| SCHEMBL2275704 | 0.68 | ALDH1A1 (0.47) | ACERENLMNAHSD17B10CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657425-A1 | Process for the preparation of chiral aminoalcohols | Degussa Aktiengesellschaft (DE) | 1995-06-14 | — | — | EP | disclosed |