Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.54 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8854725 | 0.83 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2KDM4EHTTMAPT | |
| SCHEMBL9035476 | 0.81 | LMNA (0.61) | ALDH1A1SMN1; SMN2POLBMAPTKMT2A | |
| SCHEMBL9229960 | 0.73 | ALDH1A1 (0.49) | ALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL17073180 | 0.73 | ATM (0.70) | ALDH1A1SMN1; SMN2KDM4EHTTPOLB | |
| SCHEMBL9225412 | 0.71 | KDM4E (0.55) | ALDH1A1SMN1; SMN2KDM4EPOLBMAPT | |
| SCHEMBL7575179 | 0.70 | HTT (0.54) | ALDH1A1SMN1; SMN2KDM4EHTTPOLB | |
| SCHEMBL15647612 | 0.69 | KDM4E (0.61) | ALDH1A1SMN1; SMN2KDM4EHTTPOLB | |
| SCHEMBL9225403 | 0.69 | KMT2A (0.72) | ALDH1A1SMN1; SMN2KDM4EHTTPOLB | |
| SCHEMBL6934770 | 0.68 | CETP (0.61) | ALDH1A1KDM4EHTTPOLBGAA | |
| SCHEMBL8644045 | 0.68 | ALDH1A1 (0.81) | ALDH1A1SMN1; SMN2HTTMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685470-A2 | Benzene derivatives and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1995-12-06 | — | — | EP | disclosed |