Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8854725 | 0.85 | ALDH1A1 (0.59) | MAPTSMN1; SMN2ALDH1A1GAAKMT2A | |
| SCHEMBL9225175 | 0.82 | LMNA (0.67) | LMNAMAPTSMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL9230302 | 0.81 | ALDH1A1 (0.57) | MAPTSMN1; SMN2ALDH1A1POLBGAA | |
| SCHEMBL7574965 | 0.80 | MAPT (0.51) | LMNAMAPTSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL12388226 | 0.77 | MAPT (0.56) | LMNAMAPTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL8396995 | 0.74 | NPC1 (0.72) | LMNAMAPTSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL2552295 | 0.74 | LMNA (0.82) | LMNAMAPTSMN1; SMN2L3MBTL1TDP1 | |
| Morpholine SCHEMBL7574967 | 0.74 | HCAR3 (0.55) | MAPTKMT2A | |
| SCHEMBL9231190 | 0.74 | MAPT (0.56) | LMNAMAPTSMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL7568813 | 0.72 | HCAR3 (0.69) | MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696583-A1 | Benzimidazolesulfonamide derivatives and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1996-02-14 | — | — | EP | disclosed |